Tag Archives: mouse model

Non-human primate model of the maternal infection risk factor for autism and schizophrenia

We have just published our first paper on extending the rodent model of maternal immune activation to monkeys. As repeat readers of this blog, and the accompanying book, well know, an important risk factor for both autism and schizophrenia is … Continue reading

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More evidence of immune involvement in autism and schizophrenia, and implications for therapy

Given that many studies have provided evidence that infection in  pregnant women is associated with increased risk for autism and schizophrenia in the offspring, Alan Brown and his colleagues in Finland measured the levels of C-reactive protein (CRP), an established biomarker of … Continue reading

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Pure cure for autism?

An impressive new paper is just out from Robert Naviaux, Susan Powell and colleagues at UC San Diego. They use our mouse model of the autism and schizophrenia risk factor, maternal immune activation during pregnancy, to show that a drug … Continue reading

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Another top 10 list for 2012

Elaine Hsiao’s paper also made the top 10 list of “Notable papers of 2012” from the Simons Foundation Autism Research Initiative. Her paper was coupled with the one from Derecki et al., who also reported on the efficacy of bone … Continue reading

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We’re in the top 10, as well as the top 12!

Congrats to Elaine Hsiao our super-productive graduate student who passed her exam to get her PhD at the end of 2012. Her paper, “Modeling an autism risk factor in mice leads to permanent immune dysregulation”, was just named one of the … Continue reading

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Advances presented at the recent Society for Neuroscience meeting

After 5 intensive days at the annual meeting held this year in New Orleans, things are just getting back to normal around here. Among the >28,000 participants, there were several presentations that particularly caught my eye in the areas of … Continue reading

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Our “strangest discovery”

The Director of the National Institute of Mental Health, Tom Insel, comments on relevant research advances periodically, and on Aug 24 he had this to say, “The strangest discovery of the summer may be the report of bone marrow transplants … Continue reading

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