Tag Archives: GI inflammation
Stem cell therapy for autism – first clinical trial
A paper just out from the Shenzen Beike Cell Engineering Research Institute in Guangdong, China presents the first results of a proof-of-concept, safety trial of stem cell (SC) injections in 37 autistic children. The justification for this intervention is primarily … Continue reading
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Tagged autism, autoimmune disease, cytokine, GI inflammation, health, mental-health, OCD, PANDAS, Rett syndrome, Tourette
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TEDx talk: Mind altering microbes
Our just graduated PhD student Elaine Hsiao recently gave a superb 5 minute talk at Caltech’s TEDx event on her work on gut-brain connections related to autism: Mind Altering Microbes. [click on that title to see the talk][click on the … Continue reading
“Infectious Behavior” blog – 2012 in review
4,329 films were submitted to the 2012 Cannes Film Festival. This blog had 16,000 views in 2012. If each view were a film, this blog would power 4 Film Festivals Click here to see the complete report.
Posted in General
Tagged antipsychotic, autism, autoantibodies, autoimmune disease, bipolar, cytokine, depression, diet and autism, flu, fragile x, GI inflammation, GI symptoms and autism, helminth therapy, IL-6, inflammation, influenza, leaky gut, maternal infection, mental-health, microbiome, multiple sclerosis, OCD, PANDAS, Rett syndrome, schizophrenia, stereotyped behavior, streptococcus, stress, Syndenham, Tourette
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Gastrointestinal and microbiome changes in autism?
Tony Persico and V. Napolioni have just published a review article centered around their finding that a particular molecule, p-cresol, is excreted (found in the urine) at higher levels in autistic kids than in controls. I described their initial finding … Continue reading
Annotations posted for the important NYT article
Moises Velasquez-Manoff, the author of last Sunday’s NYT article on immune-autism connections has just posted a list of references that he used to put the article together. I think he does a good job in citing relevant work. Of course, … Continue reading
Live chat on Autism Speaks Facebook Tue, 8/29
I’ll be answering questions and discussing the NYT article on immune involvement in autism tomorrow, 8/29, 3pm EDT: https://www.facebook.com/autismspeaks?ref=stream&sk=app_226961267321617 So it turned out than an hour was no where near long enough to answer all the questions. Therefore, I’ll attempt to … Continue reading
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Tagged antibiotic, antipsychotic, autism, autoantibodies, autoimmune disease, cytokine, flu, GI inflammation, GI symptoms and autism, inflammation, leaky gut, Maloney. Tourette, maternal infection, mental-health, mouse model, multiple sclerosis, OCD, PANDAS, schizophrenia, stereotyped behavior, streptococcus, Tourette
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Huge interest in NYT article: “An immune disorder at the root of autism”
Wow, amazing interest in the article by Moises Velasquez-Manoff in yesterday’s Sunday NYT (link to it is found on my Facebook page). The title is provocative and the style is very flashy and not at all scholarly or scientific. He does … Continue reading
Posted in General
Tagged autism, autoimmune disease, cytokine, GI inflammation, GI symptoms and autism, inflammation, leaky gut, maternal infection, microbiome, mouse model
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Anti-inflammatory treatments for autism
With the publication of our new paper (see the prior post), folks have asked, since bone marrow transplant (BMT) ameliorates several of the autism-like behaviors in our mouse model of maternal infection, are we saying that such transplants should be … Continue reading
Posted in General
Tagged autism, cytokine, GI inflammation, IL-6, inflammation, mental-health, OCD, Rett syndrome, socialability, stereotyped behavior
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Cluster analysis of symptoms identifies a very significant “immune group” in autism patients
The heterogeneity of symptoms among patients with autism spectrum disorder (ASD) is a major problem for researchers working on the etiology and pathology of the disorder. This diversity also poses a significant hurdle in evaluating the efficacy of potential therapies. Various … Continue reading
Whipworm intestinal parasite also helpful in human trials of Crohn’s disease, ulcerative colitis, and in diabetic mice – what about autism?
I was just contacted by Karin Hehenberger to join the Scientific Advisory Board of her company, Coronado Biosciences. This company is studying the effects of adminstering non-pathogenic whipworm ova (Trichuris suis; TSO) in a number of autoimmune diseases. They are … Continue reading
Infectious Behavior 