Tag Archives: leaky gut

Our new paper due out in Dec 5 CELL

Posted on November 23, 2013 by phpatterson

This is the paper showing probiotic therapy works in the mouse model of an autism risk factor.

Posted in General | Tagged autoantibodies, cytokine, diet and autism, GI symptoms and autism, leaky gut, maternal infection, microbiome, OCD, schizophrenia | 4 Comments

Pure cure for autism?

Posted on March 21, 2013 by phpatterson

An impressive new paper is just out from Robert Naviaux, Susan Powell and colleagues at UC San Diego. They use our mouse model of the autism and schizophrenia risk factor, maternal immune activation during pregnancy, to show that a drug … Continue reading →

Posted in General | Tagged autism, diet and autism, GI symptoms and autism, inflammation, leaky gut, maternal infection, mental-health, mitochondria, mouse model, schizophrenia, socialability, stereotyped behavior | 4 Comments

TEDx talk: Mind altering microbes

Posted on February 20, 2013 by phpatterson

Our just graduated PhD student Elaine Hsiao recently gave a superb 5 minute talk at Caltech’s TEDx event on her work on gut-brain connections related to autism: Mind Altering Microbes. [click on that title to see the talk][click on the … Continue reading →

Posted in General | Tagged autism, autoimmune disease, GI inflammation, GI symptoms and autism, leaky gut, maternal infection, mental-health, microbiome, multiple sclerosis, schizophrenia | 5 Comments

“Infectious Behavior” blog – 2012 in review

Posted on December 31, 2012 by phpatterson

4,329 films were submitted to the 2012 Cannes Film Festival. This blog had 16,000 views in 2012. If each view were a film, this blog would power 4 Film Festivals Click here to see the complete report.

Posted in General | Tagged antipsychotic, autism, autoantibodies, autoimmune disease, bipolar, cytokine, depression, diet and autism, flu, fragile x, GI inflammation, GI symptoms and autism, helminth therapy, IL-6, inflammation, influenza, leaky gut, maternal infection, mental-health, microbiome, multiple sclerosis, OCD, PANDAS, Rett syndrome, schizophrenia, stereotyped behavior, streptococcus, stress, Syndenham, Tourette | Leave a comment

Our “strangest discovery”

Posted on October 3, 2012 by phpatterson

The Director of the National Institute of Mental Health, Tom Insel, comments on relevant research advances periodically, and on Aug 24 he had this to say, “The strangest discovery of the summer may be the report of bone marrow transplants … Continue reading →

Posted in General | Tagged autism, bone marrow transplant, GI symptoms and autism, inflammation, leaky gut, maternal infection, microbiome, mouse model, NIMH | 17 Comments

Gastrointestinal and microbiome changes in autism?

Posted on September 19, 2012 by phpatterson

Tony Persico and V. Napolioni have just published a review article centered around their finding that a particular molecule, p-cresol, is excreted (found in the urine) at higher levels in autistic kids than in controls. I described their initial finding … Continue reading →

Posted in General | Tagged autism, cresol, GI inflammation, GI symptoms and autism, inflammation, leaky gut, maternal infection, mental-health, microbiome, mouse model, socialability, stereotyped behavior | 5 Comments

Live chat on Autism Speaks Facebook Tue, 8/29

Posted on August 28, 2012 by phpatterson

I’ll be answering questions and discussing the NYT article on immune involvement in autism tomorrow, 8/29, 3pm EDT: https://www.facebook.com/autismspeaks?ref=stream&sk=app_226961267321617 So it turned out than an hour was no where near long enough to answer all the questions. Therefore, I’ll attempt to … Continue reading →

Posted in General | Tagged antibiotic, antipsychotic, autism, autoantibodies, autoimmune disease, cytokine, flu, GI inflammation, GI symptoms and autism, inflammation, leaky gut, Maloney. Tourette, maternal infection, mental-health, mouse model, multiple sclerosis, OCD, PANDAS, schizophrenia, stereotyped behavior, streptococcus, Tourette | 6 Comments

Huge interest in NYT article: “An immune disorder at the root of autism”

Posted on August 28, 2012 by phpatterson

Wow, amazing interest in the article by Moises Velasquez-Manoff in yesterday’s Sunday NYT (link to it is found on my Facebook page). The title is provocative and the style is very flashy and not at all scholarly or scientific. He does … Continue reading →

Posted in General | Tagged autism, autoimmune disease, cytokine, GI inflammation, GI symptoms and autism, inflammation, leaky gut, maternal infection, microbiome, mouse model | 13 Comments

Cluster analysis of symptoms identifies a very significant “immune group” in autism patients

Posted on July 18, 2012 by phpatterson

The heterogeneity of symptoms among patients with autism spectrum disorder (ASD) is a major problem for researchers working on the etiology and pathology of the disorder. This diversity also poses a significant hurdle in evaluating the efficacy of potential therapies. Various … Continue reading →

Posted in General | Tagged autism, autoimmune disease, developmental delay, diet and autism, flu, GI inflammation, GI symptoms and autism, inflammation, influenza, leaky gut, maternal infection, mental-health, mouse model, socialability, stereotyped behavior | Leave a comment

Medical ecology, or doctors as wildlife managers

Posted on June 19, 2012 by phpatterson

Very informative and fascinating article in the NYT this morning reviewing various aspects of research on the gut microbiome, virome, and fungome. Topics include the changes in vaginal bacteria during pregnancy, in breast milk, and in infants, as well as … Continue reading →

Posted in General | Tagged antibiotic, diet and autism, GI inflammation, GI symptoms and autism, leaky gut, microbiome | 4 Comments