Tag Archives: maternal infection
Our new paper due out in Dec 5 CELL
This is the paper showing probiotic therapy works in the mouse model of an autism risk factor.
Posted in General
Tagged autoantibodies, cytokine, diet and autism, GI symptoms and autism, leaky gut, maternal infection, microbiome, OCD, schizophrenia
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We have just published our first paper on extending the rodent model of maternal immune activation to monkeys. As repeat readers of this blog, and the accompanying book, well know, an important risk factor for both autism and schizophrenia is … Continue reading
flu during pregnancy & bipolar in offspring
Readers of this book and blog are well aware that influenza infection during pregnancy increases the risk for schizophrenia and autism in the offspring. Now Alan Brown and colleagues at Columbia Univ expand that risk to bipolar disorder (BD). The … Continue reading
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Tagged bipolar, depression, flu, influenza, maternal infection, mental-health
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Placentas and autism
Several people have inquired about a new paper tying abnormalities in the placenta with an autism outcome in the offspring. This work involved a collaboration between Cheryl Walker and colleagues at UC Davis and Harvey Kliman at Yale in which … Continue reading
Posted in General
Tagged autism, cytokine, developmental delay, flu, IL-6, inflammation, influenza, maternal infection
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More evidence of immune involvement in autism and schizophrenia, and implications for therapy
Given that many studies have provided evidence that infection in pregnant women is associated with increased risk for autism and schizophrenia in the offspring, Alan Brown and his colleagues in Finland measured the levels of C-reactive protein (CRP), an established biomarker of … Continue reading
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Tagged antibiotic, antipsychotic, autism, cytokine, fragile x, inflammation, maternal infection, mental-health, mouse model, Rett syndrome
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Pure cure for autism?
An impressive new paper is just out from Robert Naviaux, Susan Powell and colleagues at UC San Diego. They use our mouse model of the autism and schizophrenia risk factor, maternal immune activation during pregnancy, to show that a drug … Continue reading
TEDx talk: Mind altering microbes
Our just graduated PhD student Elaine Hsiao recently gave a superb 5 minute talk at Caltech’s TEDx event on her work on gut-brain connections related to autism: Mind Altering Microbes. [click on that title to see the talk][click on the … Continue reading
My favorite drug & maternal inflammation risk for autism
Alan Brown, an epidemiologist at Columbia University College of Physicians and Surgeons, has provided critical evidence establishing maternal infection as a risk factor for schizophrenia in the offspring. He has now turned his attention to autism. In a paper published … Continue reading
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Tagged autism, cytokine, IL-6, inflammation, influenza, maternal infection, mental-health
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Another top 10 list for 2012
Elaine Hsiao’s paper also made the top 10 list of “Notable papers of 2012” from the Simons Foundation Autism Research Initiative. Her paper was coupled with the one from Derecki et al., who also reported on the efficacy of bone … Continue reading
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Tagged autism, cytokine, flu, inflammation, influenza, maternal infection, mental-health, mouse model, schizophrenia
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“Infectious Behavior” blog – 2012 in review
4,329 films were submitted to the 2012 Cannes Film Festival. This blog had 16,000 views in 2012. If each view were a film, this blog would power 4 Film Festivals Click here to see the complete report.
Posted in General
Tagged antipsychotic, autism, autoantibodies, autoimmune disease, bipolar, cytokine, depression, diet and autism, flu, fragile x, GI inflammation, GI symptoms and autism, helminth therapy, IL-6, inflammation, influenza, leaky gut, maternal infection, mental-health, microbiome, multiple sclerosis, OCD, PANDAS, Rett syndrome, schizophrenia, stereotyped behavior, streptococcus, stress, Syndenham, Tourette
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