Tag Archives: inflammation

Why wasn’t major depressive disorder eliminated during evolution?

My posts have overwhelmingly focused on autism and schizophrenia, but my book also covers links between immune factors and major depressive disorder (MDD). However, an email from science writer Virginia Hughes stimulates me to write about MDD here. Ginny reminded … Continue reading

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We’re in the top 10, as well as the top 12!

Congrats to Elaine Hsiao our super-productive graduate student who passed her exam to get her PhD at the end of 2012. Her paper, “Modeling an autism risk factor in mice leads to permanent immune dysregulation”, was just named one of the … Continue reading

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PANDAS child trapped in Boston Children’s Hospital

Amazing story in the Boston Globe about what can happen if a child with PANDAS is put into the wrong hospital – one that does not agree with the PANDAS diagnosis. PANDAS is short for Pediatric Autoimmune Neuropsychiatric Disorders Associated with … Continue reading

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Advances presented at the recent Society for Neuroscience meeting

After 5 intensive days at the annual meeting held this year in New Orleans, things are just getting back to normal around here. Among the >28,000 participants, there were several presentations that particularly caught my eye in the areas of … Continue reading

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Our “strangest discovery”

The Director of the National Institute of Mental Health, Tom Insel, comments on relevant research advances periodically, and on Aug 24 he had this to say, “The strangest discovery of the summer may be the report of bone marrow transplants … Continue reading

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The placenta and autism risk, and our genius collaborator

Elaine Hsiao and I just published an invited note on the SFARI (Simons Foundation autism Research Initiative) site regarding the role of the placenta in autism. The title they place on the article, “Placenta plays potent role in autism risk”, is … Continue reading

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Toxo infection increases risk for suicide

At the PANDAS meeting last week in Irvine, my Swedish publisher, Gunilla Gerland of Pauvus Utbildning, told me about 2 new articles on Toxoplasma gondii infection, which are of interest in light of the discussion in Chap. 5 of my … Continue reading

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Gastrointestinal and microbiome changes in autism?

Tony Persico and V. Napolioni have just published a review article centered around their finding that a particular molecule, p-cresol, is excreted (found in the urine) at higher levels in autistic kids than in controls. I described their initial finding … Continue reading

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New review of our books

Excerpt from review of my book and the one with Alan Brown, “Origins of Schizophrenia”, by Dolores Malaspina, a Professor of Psychiatry at the New York University School of Medicine, just published in the American Journal of Psychiatry (169:998, September … Continue reading

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Inflammation and heart attack – implications for autism?

Interesting post from asdresearchinitiative.

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