Tag Archives: autoimmune disease

Huge interest in NYT article: “An immune disorder at the root of autism”

Wow, amazing interest in the article by Moises Velasquez-Manoff in yesterday’s Sunday NYT (link to it is found on my Facebook page). The title is provocative and the style is very flashy and not at all scholarly or scientific. He does … Continue reading

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Cluster analysis of symptoms identifies a very significant “immune group” in autism patients

The heterogeneity of symptoms among patients with autism spectrum disorder (ASD) is a major problem for researchers working on the etiology and pathology of the disorder. This diversity also poses a significant hurdle in evaluating the efficacy of potential therapies. Various … Continue reading

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Whipworm intestinal parasite also helpful in human trials of Crohn’s disease, ulcerative colitis, and in diabetic mice – what about autism?

I was just contacted by Karin Hehenberger to join the Scientific Advisory Board of her company, Coronado Biosciences. This company is studying the effects of adminstering non-pathogenic whipworm ova (Trichuris suis; TSO) in a number of autoimmune diseases. They are … Continue reading

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Parasite treatment for multiple sclerosis and…

In chapter 7 of my book, and in my post of Dec 2, 2011, I noted how the hygiene hypothesis is used to explain the relatively recent, serious rise in auto-immune disorders. This is illustrated by the correlation between the … Continue reading

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Microglia eating synapses in autism?

It has been known since the groundbreaking work of Carlos Pardo (see his profile in my book) that the brain in autism is in an immune-activated state. In postmortem samples, there is evidence of microglial activation and cytokine increases. The … Continue reading

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Of PANDAS and rats

In a post on 4/6/12, I reviewed a paper by Zhang et al. that provided evidence that anti-streptococcus antibodies can penetrate into the brain and possibly excite neurons in areas relevant for behaviors relevant for PANDAS and OCD. The authors … Continue reading

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New immune-related autism reports from IMFAR

asdresearchinitiative points out on his/her blog 5 abstracts from the current International Meeting for Autism Research (IMFAR), run by the International Society for Autism Research (INSAR). The abstracts are all from UC Davis/MIND Institute. One puzzling finding in the Schwartzer … Continue reading

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Ever more immune links with schizophrenia

Last year, Brian Miller and colleagues at the Georgia Health Sciences University reported a meta-analysis of cytokine alterations in the serum of schizophrenia (Sz) subjects. This type of study synthesizes findings from many papers in the literature, in this case … Continue reading

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Autism-schizophrenia overlap

Thanks to ASDresearchinitiative for pointing out a new article on diseases that are co-morbid with autism. The findings (simplified by me): 19% of ASD patients had epilepsy as compared to 2% in the overall hospital population, 2.4% of ASD with schizophrenia vs. … Continue reading

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